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Shabnam Peyvandi


  • Associate Professor, Pediatrics
  • Associate Director, UCSF Fetal Cardiovascular Program
  • Pediatric Cardiologist


Dr. Shabnam Peyvandi is an assistant professor in the division of pediatric cardiology at UCSF. Her clinical interests include fetal diagnosis and management of congenital heart disease in addition to transthoracic and transesophageal echocardiography. She also heads the pediatric cardiovascular genetics program at UCSF, specializing in cardiac genetic issues from fetal development to adulthood. She collaborates with the UCSF Fetal Treatment Center to help coordinate care for fetuses diagnosed with heart problems.

Dr. Peyvandi received her medical degree from New York Medical College and completed her pediatrics residency at Children’s Hospital of Los Angeles. She then completed a cardiology fellowship and an advanced echocardiography and fetal cardiology fellowship at The Children’s Hospital of Philadelphia before joining UCSF in the fall of 2013. Dr. Peyvandi’s primary research interests include cardiovascular genetics and fetal markers of neurodevelopmental outcomes in patients with congenital heart disease.

Education & Training

  • UCSF, San Francisco Master's of Clinical Research
  • Children's Hospital of Philadelphia, Philadelphia Non-invasive and Fetal Cardiology
  • Children's Hospital of Philadelphia, Philadelphia Pediatric Cardiology Fellowship
  • Children's Hospital of Los Angeles, Los Angeles, CA Pediatrics Residency
  • New York Medical College, New York Medicine

Clincial Trials

Research Activities & Funding

  • The Risk of Acquired Neonatal Significant brain Injury during perinatal Transition in Congenital Heart Disease: TRANSIT CHD study

    Sponsor: NIH R01NS125404

    Role: Principal Investigator

  • Early brain networks that predict school-age neurodevelopmental outcomes in critical congenital heart disease

    Sponsor: Children's Heart Foundation A138402

    Role: Principal Investigator

  • Fetal markers of neurodevelopmental outcomes in congenital heart disease

    Sponsor: NIH K23NS099422

    Role: Principal Investigator


  • Young BT, Baer RJ, Chambers CD, Peyvandi S, Jelliffe-Pawlowski LL, Steurer MA. What drives outcomes in infants of mothers with congenital heart disease? A mediation analysis. J Perinatol. 2023 Oct 19. PubMed
  • Juergensen S, Liu J, Xu D, Zhao Y, Moon-Grady AJ, Glenn O, McQuillen P, Peyvandi S. Fetal circulatory physiology and brain development in complex congenital heart disease: A multi-modal imaging study. Prenat Diagn. 2023 Oct 10. PubMed
  • Ortinau CM, Wypij D, Ilardi D, Rofeberg V, Miller TA, Donohue J, Reichle G, Seed M, Elhoff J, Alexander N, Allen K, Anton C, Bear L, Boucher G, Bragg J, Butcher J, Chen V, Glotzbach K, Hampton L, Lee CK, Ly LG, Marino BS, Martinez-Fernandez Y, Monteiro S, Ortega C, Peyvandi S, Raiees-Dana H, Rollins CK, Sadhwani A, Sananes R, Sanz JH, Schultz AH, Sood E, Tan A, Willen E, Wolfe KR, Goldberg CS. Factors Associated With Attendance for Cardiac Neurodevelopmental Evaluation. Pediatrics. 2023 Sep 01; 152(3). PubMed
  • Parekh S, Ochotny R, Lazow SP, Ben-Ishay O, Aribindi V, Pluchinotta FR, Tworetzky W, Buchmiller TL, Peyvandi S, Moon-Grady AJ. High prevalence of left superior vena cava and congenital heart disease in patients with pre- and postnatally diagnosed esophageal atresia/tracheoesophageal fistula. Ultrasound Obstet Gynecol. 2023 Sep; 62(3):439-440. PubMed
  • Steurer MA, McCulloch C, Santana S, Collins JW, Branche T, Costello JM, Peyvandi S. Disparities in 1-Year-Mortality in Infants With Cyanotic Congenital Heart Disease: Insights From Contemporary National Data. Circ Cardiovasc Qual Outcomes. 2023 07; 16(7):e009981. PubMed
  • Lopez KN, Morris SA, Krishnan A, Jacobs MB, Bhat AH, Chelliah A, Chiu JS, Cuneo BF, Freire G, Hornberger LK, Howley L, Husain N, Ikemba C, Kavanaugh-McHugh A, Kutty S, Lee C, McBrien A, Michelfelder EC, Pinto NM, Schwartz R, Stern KWD, Taylor C, Thakur V, Tworetzky W, Wittlieb-Weber C, Woldu K, Donofrio MT, Peyvandi S, Fetal Heart Society Research Collaborative. Associations Between Maternal Sociodemographics and Hospital Mortality in Newborns With Prenatally Diagnosed Hypoplastic Left Heart Syndrome. Circulation. 2023 07 18; 148(3):283-285. PubMed
  • Moon-Grady AJ, Donofrio MT, Gelehrter S, Hornberger L, Kreeger J, Lee W, Michelfelder E, Morris SA, Peyvandi S, Pinto NM, Pruetz J, Sethi N, Simpson J, Srivastava S, Tian Z. Guidelines and Recommendations for Performance of the Fetal Echocardiogram: An Update from the American Society of Echocardiography. J Am Soc Echocardiogr. 2023 Jul; 36(7):679-723. PubMed
  • Vassar R, Peyvandi S, Gano D, Cox S, Zetino Y, Miller S, McQuillen P. Critical congenital heart disease beyond HLHS and TGA: neonatal brain injury and early neurodevelopment. Pediatr Res. 2023 08; 94(2):691-698. PubMed
  • Sanz JH, Cox S, Donofrio MT, Ishibashi N, McQuillen P, Peyvandi S, Schlatterer S. [Formula: see text] Trajectories of neurodevelopment and opportunities for intervention across the lifespan in congenital heart disease. Child Neuropsychol. 2023 11; 29(7):1128-1154. PubMed
  • Peyvandi S, Xu D, Barkovich AJ, Gano D, Chau V, Reddy VM, Selvanathan T, Guo T, Gaynor JW, Seed M, Miller SP, McQuillen P. Declining Incidence of Postoperative Neonatal Brain Injury in Congenital Heart Disease. J Am Coll Cardiol. 2023 01 24; 81(3):253-266. PubMed
  • Arya B, Donofrio MT, Freud LR, Hornberger LK, Moon-Grady AJ, Morris SA, Pinto N, Simpson LL, Cuneo BF, Divanovic A, Jaeggi E, Peyvandi S, Puchalski MD, Rychik J, Schidlow DN, Srivastava S, Tacy TA, Tworetzky W, Walsh MJ. Implications of United States Supreme Court's ruling on Dobbs vs Jackson Women's Health Organization: perspective of physicians caring for critically ill fetuses and newborns. Ultrasound Obstet Gynecol. 2022 12; 60(6):812-813. PubMed
  • Peyvandi S, Rollins C. Fetal Brain Development in Congenital Heart Disease. Can J Cardiol. 2023 02; 39(2):115-122. PubMed
  • Nawaytou H, Springston C, Lazar A, Keller S, Hogan W, Cresalia N, Peyvandi S, Cocalis M, Moon-Grady A, Brook M. A Measurement-Based Protocol Improves Interrater Agreement and Accuracy of Right Ventricular Systolic Pressure Assessment by Echocardiography in Children: A Call for Quality Improvement. J Am Soc Echocardiogr. 2022 10; 35(10):1091-1100. PubMed
  • Santana S, Peyvandi S, Costello JM, Baer RJ, Collins JW, Branche T, Jelliffe-Pawlowski LL, Steurer MA. Adverse Maternal Fetal Environment Partially Mediates Disparate Outcomes in Non-White Neonates with Major Congenital Heart Disease. J Pediatr. 2022 12; 251:82-88.e1. PubMed
  • Steurer MA, Schuhmacher K, Savla JJ, Banerjee M, Chanani NK, Eckhauser A, Elhoff J, Jacobs JP, Mikesell K, Peyvandi S, Romano J, Zhang W, Gaynor JW, Tabbutt S. Fetal growth and gestational age improve outcome predictions in neonatal heart surgery. J Thorac Cardiovasc Surg. 2022 12; 164(6):2003-2012.e1. PubMed
  • Lopez KN, Baker-Smith C, Flores G, Gurvitz M, Karamlou T, Nunez Gallegos F, Pasquali S, Patel A, Peterson JK, Salemi JL, Yancy C, Peyvandi S, American Heart Association Congenital Cardiac Defects Committee of the Council on Lifelong Congenita. Addressing Social Determinants of Health and Mitigating Health Disparities Across the Lifespan in Congenital Heart Disease: A Scientific Statement From the American Heart Association. J Am Heart Assoc. 2022 04 19; 11(8):e025358. PubMed
  • Sunderji S, Peyvandi S, Jaeggi E, Szwast A, Ryan G, Tessier F, Siddiqui S, Cuneo B, Sheth S, Treadwell M, Frommelt M, Turan S, Copel J, Emery S, Rand L, Moon-Grady AJ, North American Fetal Therapy Network (NAFTNet). NAFTNet retrospective report on the treatment of anti-Ro/SSA mediated fetal heart block with dexamethasone. J Matern Fetal Neonatal Med. 2022 Dec; 35(25):9263-9270. PubMed
  • Ramirez A, Peyvandi S, Cox S, Gano D, Xu D, Tymofiyeva O, McQuillen PS. Neonatal brain injury influences structural connectivity and childhood functional outcomes. PLoS One. 2022; 17(1):e0262310. PubMed
  • Parekh SA, Cox SM, Barkovich AJ, Chau V, Steurer MA, Xu D, Miller SP, McQuillen PS, Peyvandi S. The Effect of Size and Asymmetry at Birth on Brain Injury and Neurodevelopmental Outcomes in Congenital Heart Disease. Pediatr Cardiol. 2022 Apr; 43(4):868-877. PubMed
  • Steurer MA, Baer RJ, Chambers CD, Costello J, Franck LS, McKenzie-Sampson S, Pacheco-Werner TL, Rajagopal S, Rogers EE, Rand L, Jelliffe-Pawlowski LL, Peyvandi S. Mortality and Major Neonatal Morbidity in Preterm Infants with Serious Congenital Heart Disease. J Pediatr. 2021 12; 239:110-116.e3. PubMed
  • Afshar Y, Hogan WJ, Conturie C, Sunderji S, Duffy JY, Peyvandi S, Boe NM, Melber D, Fajardo VM, Tandel MD, Holliman K, Kwan L, Satou G, Moon-Grady AJ. Multi-Institutional Practice-Patterns in Fetal Congenital Heart Disease Following Implementation of a Standardized Clinical Assessment and Management Plan. J Am Heart Assoc. 2021 08 03; 10(15):e021598. PubMed
  • Chelliah A, Moon-Grady AJ, Peyvandi S, Chiu JS, Bost JE, Schidlow D, Carroll SJ, Davey B, Divanovic A, Hornberger L, Howley LW, Kavanaugh-McHugh A, Kovalchin JP, Levasseur SM, Lindblade CL, Morris SA, Ngwezi D, Pruetz JD, Puchalski MD, Rychik J, Samai C, Tacy TA, Tworetzky W, Vernon MM, Yeh J, Donofrio MT. Contemporary Outcomes in Tetralogy of Fallot With Absent Pulmonary Valve After Fetal Diagnosis. J Am Heart Assoc. 2021 06 15; 10(12):e019713. PubMed
  • Krishnan A, Jacobs MB, Morris SA, Peyvandi S, Bhat AH, Chelliah A, Chiu JS, Cuneo BF, Freire G, Hornberger LK, Howley L, Husain N, Ikemba C, Kavanaugh-McHugh A, Kutty S, Lee C, Lopez KN, McBrien A, Michelfelder EC, Pinto NM, Schwartz R, Stern KWD, Taylor C, Thakur V, Tworetzky W, Wittlieb-Weber C, Woldu K, Donofrio MT, Fetal Heart Society. Impact of Socioeconomic Status, Race and Ethnicity, and Geography on Prenatal Detection of Hypoplastic Left Heart Syndrome and Transposition of the Great Arteries. Circulation. 2021 05 25; 143(21):2049-2060. PubMed
  • Hogan WJ, Moon-Grady AJ, Zhao Y, Cresalia NM, Nawaytou H, Quezada E, Brook M, McQuillen P, Peyvandi S. Fetal cerebrovascular response to maternal hyperoxygenation in congenital heart disease: effect of cardiac physiology. Ultrasound Obstet Gynecol. 2021 05; 57(5):769-775. PubMed
  • Kosiv KA, Moon-Grady A, Hogan W, Keller R, Rapoport R, Rogers E, Feldstein VA, Lee H, Peyvandi S. Fetal cerebrovascular impedance is reduced in left congenital diaphragmatic hernia. Ultrasound Obstet Gynecol. 2021 03; 57(3):386-391. PubMed
  • Steurer MA, Peyvandi S, Costello JM, Moon-Grady AJ, Habib RH, Hill KD, Jacobs ML, Jelliffe-Pawlowski LL, Keller RL, Pasquali SK, Reddy VM, Tabbutt S, Rajagopal S. Association between Z-score for birth weight and postoperative outcomes in neonates and infants with congenital heart disease. J Thorac Cardiovasc Surg. 2021 12; 162(6):1838-1847.e4. PubMed
  • Peyvandi S, Xu D, Wang Y, Hogan W, Moon-Grady A, Barkovich AJ, Glenn O, McQuillen P, Liu J. Fetal Cerebral Oxygenation Is Impaired in Congenital Heart Disease and Shows Variable Response to Maternal Hyperoxia. J Am Heart Assoc. 2021 01 05; 10(1):e018777. PubMed
  • Peyvandi S, Lim JM, Marini D, Xu D, Reddy VM, Barkovich AJ, Miller S, McQuillen P, Seed M. Fetal brain growth and risk of postnatal white matter injury in critical congenital heart disease. J Thorac Cardiovasc Surg. 2021 09; 162(3):1007-1014.e1. PubMed
  • Lin Y, Hogan W, Stillwell K, Moore P, Peyvandi S, Amin E, Quezada E. Giant Neonatal Pulmonary Arteriovenous Malformation: An Imaging and Management Challenge. CASE (Phila). 2020 Dec; 4(6):526-530. PubMed
  • Peyvandi S, Baer RJ, Chambers CD, Norton ME, Rajagopal S, Ryckman KK, Moon-Grady A, Jelliffe-Pawlowski LL, Steurer MA. Environmental and Socioeconomic Factors Influence the Live-Born Incidence of Congenital Heart Disease: A Population-Based Study in California. J Am Heart Assoc. 2020 04 21; 9(8):e015255. PubMed
  • O'Byrne ML, Peyvandi S. Decisions, Decisions, Decisions…: A Novel Approach Helps Evaluate Potential Benefit of Fetal Aortic Valvuloplasty. Circ Cardiovasc Qual Outcomes. 2020 04; 13(4):e006636. PubMed
  • Steurer MA, Peyvandi S, Baer RJ, Oltman SP, Chambers CD, Norton ME, Ryckman KK, Moon-Grady AJ, Keller RL, Shiboski SC, Jelliffe-Pawlowski LL. Impaired Fetal Environment and Gestational Age: What Is Driving Mortality in Neonates With Critical Congenital Heart Disease? J Am Heart Assoc. 2019 11 19; 8(22):e013194. PubMed
  • Hsieh A, Tabbutt S, Xu D, Barkovich AJ, Miller S, McQuillen P, Peyvandi S. Impact of Perioperative Brain Injury and Development on Feeding Modality in Infants With Single Ventricle Heart Disease. J Am Heart Assoc. 2019 05 21; 8(10):e012291. PubMed
  • Peyvandi S, McQuillen PS. Commentary: Is the brain spared when the heart is broken? J Thorac Cardiovasc Surg. 2019 05; 157(5):1994-1995. PubMed
  • Peyvandi S, Baer RJ, Moon-Grady AJ, Oltman SP, Chambers CD, Norton ME, Rajagopal S, Ryckman KK, Jelliffe-Pawlowski LL, Steurer MA. Socioeconomic Mediators of Racial and Ethnic Disparities in Congenital Heart Disease Outcomes: A Population-Based Study in California. J Am Heart Assoc. 2018 10 16; 7(20):e010342. PubMed
  • Steurer MA, Baer RJ, Burke E, Peyvandi S, Oltman S, Chambers CD, Norton ME, Rand L, Rajagopal S, Ryckman KK, Feuer SK, Liang L, Paynter RA, McCarthy M, Moon-Grady AJ, Keller RL, Jelliffe-Pawlowski LL. Effect of Fetal Growth on 1-Year Mortality in Neonates With Critical Congenital Heart Disease. J Am Heart Assoc. 2018 09 04; 7(17):e009693. PubMed
  • Moon-Grady AJ, Peyvandi S. Measuring Up Before Birth: The New Normal. Circ Cardiovasc Imaging. 2018 07; 11(7):e008008. PubMed
  • Peyvandi S, Donofrio MT. Circulatory Changes and Cerebral Blood Flow and Oxygenation During Transition in Newborns With Congenital Heart Disease. Semin Pediatr Neurol. 2018 12; 28:38-47. PubMed
  • Guo T, Chau V, Peyvandi S, Latal B, McQuillen PS, Knirsch W, Synnes A, Feldmann M, Naef N, Chakravarty MM, De Petrillo A, Duerden EG, Barkovich AJ, Miller SP. White matter injury in term neonates with congenital heart diseases: Topology & comparison with preterm newborns. Neuroimage. 2019 01 15; 185:742-749. PubMed
  • Peyvandi S, Latal B, Miller SP, McQuillen PS. The neonatal brain in critical congenital heart disease: Insights and future directions. Neuroimage. 2019 01 15; 185:776-782. PubMed
  • Peyvandi S, Chau V, Guo T, Xu D, Glass HC, Synnes A, Poskitt K, Barkovich AJ, Miller SP, McQuillen PS. Neonatal Brain Injury and Timing of Neurodevelopmental Assessment in Patients With Congenital Heart Disease. J Am Coll Cardiol. 2018 05 08; 71(18):1986-1996. PubMed
  • Karamlou T, Peyvandi S, Federman M, Goff D, Murthy R, Kumar SR, Southwest Congenital Cardiac Consortium. Resolving the Fontan paradox: Addressing socioeconomic and racial disparities in patients with a single ventricle. J Thorac Cardiovasc Surg. 2018 04; 155(4):1727-1731. PubMed
  • Steurer MA, Baer RJ, Keller RL, Oltman S, Chambers CD, Norton ME, Peyvandi S, Rand L, Rajagopal S, Ryckman KK, Moon-Grady AJ, Jelliffe-Pawlowski LL. Gestational Age and Outcomes in Critical Congenital Heart Disease. Pediatrics. 2017 Oct; 140(4). PubMed
  • Peyvandi S, Kim H, Lau J, Barkovich AJ, Campbell A, Miller S, Xu D, McQuillen P. The association between cardiac physiology, acquired brain injury, and postnatal brain growth in critical congenital heart disease. J Thorac Cardiovasc Surg. 2018 01; 155(1):291-300.e3. PubMed
  • Hinkle KA, Peyvandi S, Stiver C, Killen SAS, Weng HY, Etheridge SP, Puchalski MD. Postnatal Outcomes of Fetal Supraventricular Tachycardia: a Multicenter Study. Pediatr Cardiol. 2017 Oct; 38(7):1317-1323. PubMed
  • Adamson G, Karamlou T, Moore P, Natal-Hernandez L, Tabbutt S, Peyvandi S. Coarctation Index Predicts Recurrent Aortic Arch Obstruction Following Surgical Repair of Coarctation of the Aorta in Infants. Pediatr Cardiol. 2017 Aug; 38(6):1241-1246. PubMed
  • Steurer MA, Peyvandi S, Baer RJ, MacKenzie T, Li BC, Norton ME, Jelliffe-Pawlowski LL, Moon-Grady AJ. Epidemiology of Live Born Infants with Nonimmune Hydrops Fetalis-Insights from a Population-Based Dataset. J Pediatr. 2017 08; 187:182-188.e3. PubMed
  • Lodin D, Mavrothalassitis O, Haberer K, Sunderji S, Quek RGW, Peyvandi S, Moon-Grady A, Karamlou T. Revisiting the utility of technical performance scores following tetralogy of Fallot repair. J Thorac Cardiovasc Surg. 2017 08; 154(2):585-595.e3. PubMed
  • Peyvandi S, Nguyen TA, Almeida-Jones M, Boe N, Rhee L, Anton T, Sklansky M, Tarsa M, Satou G, Moon-Grady AJ, University of California Fetal Consortium (UCfC). Timing and Mode of Delivery in Prenatally Diagnosed Congenital Heart Disease- an Analysis of Practices within the University of California Fetal Consortium (UCfC). Pediatr Cardiol. 2017 Mar; 38(3):588-595. PubMed
  • Beattie M, Peyvandi S, Ganesan S, Moon-Grady A. Toward Improving the Fetal Diagnosis of Coarctation of the Aorta. Pediatr Cardiol. 2017 Feb; 38(2):344-352. PubMed
  • Peyvandi S, De Santiago V, Chakkarapani E, Chau V, Campbell A, Poskitt KJ, Xu D, Barkovich AJ, Miller S, McQuillen P. Association of Prenatal Diagnosis of Critical Congenital Heart Disease With Postnatal Brain Development and the Risk of Brain Injury. JAMA Pediatr. 2016 Apr; 170(4):e154450. PubMed
  • Dayan JG, Peyvandi S, Moon-Grady AJ. Pulmonary Atresia With an Intact Ventricular Septum in the Setting of D-Transposition of the Great Arteries With a Hypoplastic Left Ventricle: Fetal Diagnosis. J Ultrasound Med. 2015 Dec; 34(12):2313-5. PubMed
  • Nawaytou HM, Peyvandi S, Brook MM, Silverman N, Moon-Grady AJ. Right Ventricular Systolic-to-Diastolic Time Index: Hypoplastic Left Heart Fetuses Differ Significantly from Normal Fetuses. J Am Soc Echocardiogr. 2016 Feb; 29(2):143-9. PubMed
  • Karamlou T, Peyvandi S. Hybrid versus Norwood: "Fifty shades of grey". J Thorac Cardiovasc Surg. 2015 Sep; 150(3):456-7. PubMed
  • Peyvandi S, Feldstein VA, Hirose S, Rand L, Brook MM, Moon-Grady AJ. Twin-reversed arterial perfusion sequence associated with decreased fetal cerebral vascular impedance. Ultrasound Obstet Gynecol. 2015 Apr; 45(4):447-51. PubMed
  • Derderian SC, Jeanty C, Fleck SR, Cheng LS, Peyvandi S, Moon-Grady AJ, Farrell J, Hirose S, Gonzalez J, Keller RL, MacKenzie TC. The many faces of hydrops. J Pediatr Surg. 2015 Jan; 50(1):50-4; discussion 54. PubMed
  • Peyvandi S, Rychik J, Zhang X, Shea JA, Goldmuntz E. Preconceptual Folic Acid Use and Recurrence Risk Counseling for Congenital Heart Disease. Congenit Heart Dis. 2015 May-Jun; 10(3):219-25. PubMed
  • Peyvandi S, Ingall E, Woyciechowski S, Garbarini J, Mitchell LE, Goldmuntz E. Risk of congenital heart disease in relatives of probands with conotruncal cardiac defects: an evaluation of 1,620 families. Am J Med Genet A. 2014 Jun; 164A(6):1490-5. PubMed
  • Peyvandi S, Rychik J, McCann M, Soffer D, Tian Z, Szwast A. Pulmonary artery blood flow patterns in fetuses with pulmonary outflow tract obstruction. Ultrasound Obstet Gynecol. 2014 Mar; 43(3):297-302. PubMed
  • Peyvandi S, Lupo PJ, Garbarini J, Woyciechowski S, Edman S, Emanuel BS, Mitchell LE, Goldmuntz E. 22q11.2 deletions in patients with conotruncal defects: data from 1,610 consecutive cases. Pediatr Cardiol. 2013 Oct; 34(7):1687-94. PubMed
  • Collins RT, Peyvandi S, Cohen MS. Atrioventricular valve dyssynchrony resulting from severe mitral regurgitation. Circulation. 2011 Feb 15; 123(6):686-90. PubMed
  • Agha-Hosseini M, Aleyaseen A, Peyvandi S, Kasha L. Comparison of pregnancy and implantation rates in zygote intrafallopian transfer and uterine embryo transfer for nontubal infertility. East Mediterr Health J. 2010 Jan; 16(1):29-33. PubMed
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