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Nasim Sobhani

MD

  • Assistant Professor, Ob/Gyn, Reproductive Sciences
  • Perinatologist

Biography

Dr. Nasim Sobhani is a perinatologist, an obstetrician who specializes in care during high-risk pregnancies. She provides comprehensive care for women with preexisting conditions that can affect pregnancy and for women with pregnancy-specific health conditions. She also cares for developing fetuses when genetic or structural conditions have been diagnosed in utero. She sees patients in both the hospital and the clinic. Dr. Sobhani serves as the medical director of the Endocrine, Diabetes, and Pregnancy Program, which is responsible for overseeing the care of all pregnant individuals with pre-existing and gestational diabetes at UCSF. As the most common medical complication of pregnancy, diabetes contributes to significant increases in the risk of adverse maternal, obstetric, and neonatal outcomes. Thoughtful clinical research is needed to optimize the care of pregnant people living with diabetes. Dr. Sobhani’s research efforts examine how to diagnose and manage gestational diabetes; how to improve perinatal outcomes for pregnancies with type 1 and type 2 diabetes; and how to leverage emerging diabetes technology in the pregnant population. Dr. Sobhani earned her medical degree at the University of Texas Southwestern Medical School. She completed a residency in obstetrics and gynecology at the University of Washington, followed by a fellowship in maternal-fetal medicine at UCSF.

Education & Training

  • UCSF Maternal-Fetal Medicine
  • University of Washington Obstetrics and Gynecology
  • UT Southwestern Medical School

Clinical Trials

Publications

  • Venkatesh KK, MacPherson C, Clifton RG, Powe CE, Bartholomew A, Gregory D, Trinh A, McAlearney AS, Fiechtner LG, Catalano P, Rice D, Cross S, Kutay H, Gabbe S, Grobman WA, Costantine MM, Battarbee AN, Boggess K, Katukuri V, Eichelberger K, Esakoff T, Feghali MN, Harper L, Kaimal A, Kole-White M, Mendez-Figueroa H, Mlynarczyk M, Sciscione A, Shook L, Sobhani NC, Stamilio DM, Werner E, Wiegand S, Zera CA, Zork NM, Saade G, Landon MB. Comparative effectiveness trial of metformin versus insulin for the treatment of gestational diabetes in the USA: clinical trial protocol for the multicentre DECIDE study. BMJ Open. 2024 Sep 24; 14(9):e091176. PubMed
  • Sobhani NC, Han CS, Sarker MR, Shah S, Ramos GA. Use of a Commercially Available Automated Insulin Delivery System for the Management of Type 1 Diabetes in Pregnancy. J Diabetes Sci Technol. 2024 Sep 10; 19322968241279569. PubMed
  • Sobhani NC, Watson K, Kannan A, Patzek S. Method of insulin delivery does not affect perinatal outcomes with type 1 diabetes mellitus. Am J Obstet Gynecol MFM. 2024 Oct; 6(10):101462. PubMed
  • Walia A, Friedman AM, Sobhani NC, Wen T. Readmission Rates After Expedited Postpartum Discharge. Obstet Gynecol. 2024 Sep 01; 144(3):421-429. PubMed
  • Wen T, Friedman AM, Gyamfi-Bannerman C, Powe CE, Sobhani NC, Ramos GA, Gabbe S, Landon MB, Grobman WA, Venkatesh KK. Diabetic Ketoacidosis and Adverse Outcomes Among Pregnant Individuals With Pregestational Diabetes in the United States, 2010-2020. Obstet Gynecol. 2024 Jul 11. PubMed
  • Agarwal A, Duan R, Sobhani NC, Sabanayagam A, Marcus GM, Gurvitz M. Health Service Use and Costs During Pregnancy Among Privately Insured Individuals With Congenital Heart Disease. JAMA Netw Open. 2024 May 01; 7(5):e2410763. PubMed
  • Levy RA, Diala PC, Rothschild HT, Correa J, Lehrman E, Markley JC, Poder L, Rabban J, Chen LM, Gras J, Sobhani NC, Cassidy AG, Chapman JS. Roadmap to safety: a single center study of evidence-informed approach to placenta accreta spectrum. Front Surg. 2024; 11:1347549. PubMed
  • Tinajero Y, Parikh NI, Harris IS, Gonzalez JM, Agarwal A, Sobhani NC. Immediate Postpartum Breastfeeding following Pregnancy with Cardiac Disease. Am J Perinatol. 2024 Oct; 41(14):2029-2032. PubMed
  • Sobhani NC, Goemans S, Nguyen A, Chambers ME, Richley M, Gabby LC, Field N, Han CS, Ramos GA. Continuous glucose monitoring in pregnancies with type 1 diabetes: small increases in time-in-range improve maternal and perinatal outcomes. Am J Obstet Gynecol. 2024 Oct; 231(4):467.e1-467.e8. PubMed
  • McClelland B, Ponting C, Levy C, Mah R, Moran P, Sobhani NC, Felder J. Viewpoint: Challenges and strategies for engaging participants in videoconferencing appointments. Contemp Clin Trials. 2024 02; 137:107425. PubMed
  • Shao SJ, Cassidy AG, Alanizi A, Agarwal A, Sobhani NC. Contraceptive counseling and choices in pregnancies with maternal cardiac disease. J Matern Fetal Neonatal Med. 2023 Dec; 36(1):2217318. PubMed
  • Walia A, Berger VK, Gonzalez JM, Sobhani NC. Mode of delivery and neonatal outcomes with early preterm severe preeclampsia: does fetal growth restriction matter? J Matern Fetal Neonatal Med. 2023 Dec; 36(1):2208251. PubMed
  • Kopp CM, Sobhani NC, Baker B, Tapia K, Jain R, Hitti J, Roxby AC. Antiretroviral Regimen and Pregnancy Outcomes of Women Living with HIV in a US Cohort. Infect Dis Clin Pract (Baltim Md). 2023 Nov; 31(6). PubMed
  • Schultz H, Sobhani NC, Blissett S, Yogeswaran V, Hong J, Harris IS, Parikh N, Gonzalez J, Agarwal A. Cardiovascular events more than 6 months after pregnancy in patients with congenital heart disease. Open Heart. 2023 09; 10(2). PubMed
  • Shao SJ, Teal EN, Lewkowitz AK, Gaw SL, Sobhani NC. Validated Calculators Predicting Cesarean Delivery After Induction: Accuracy in an External Population. Obstet Gynecol. 2023 Jul 01; 142(1):99-107. PubMed
  • Blauvelt CA, Sobhani NC, Andrikopoulou M, Friedman AM, Gonzalez-Velez JM, Wen T. Corrigendum to Trends in attempted vaginal delivery among pregnancies complicated by fetal myelomeningocele in the United States. American Journal of Obstetrics & Gynecology MFM. Volume 5, Issue 4, April 2023, 100902. Am J Obstet Gynecol MFM. 2023 Jun; 5(6):100975. PubMed
  • Sobhani NC, Killion M, Patzek S. Use of Open-Source Automated Insulin Delivery Systems in Pregnancies With Type 1 Diabetes. J Diabetes Sci Technol. 2023 07; 17(4):1126-1128. PubMed
  • Sobhani NC, Corbetta-Rastelli CM, Agarwal A, D'Alton ME, Friedman AM, Wen T. Delivery trends and obstetric outcomes in patients with Fontan circulation. Am J Obstet Gynecol MFM. 2023 05; 5(5):100921. PubMed
  • Blauvelt CA, Sobhani NC, Andrikopoulou M, Friedman AM, Gonzalez-Velez JM, Wen T. Trends in attempted vaginal delivery among pregnancies complicated by fetal myelomeningocele in the United States. Am J Obstet Gynecol MFM. 2023 04; 5(4):100902. PubMed
  • Corbetta-Rastelli CM, Friedman AM, Sobhani NC, Arditi B, Goffman D, Wen T. Postpartum Hemorrhage Trends and Outcomes in the United States, 2000-2019. Obstet Gynecol. 2023 01 01; 141(1):152-161. PubMed
  • Wen T, Baer RJ, Oltman S, Sobhani NC, Venkatesh KK, Friedman AM, Jelliffe-Pawlowski LL. Development of a risk prediction score for acute postpartum care utilization. J Matern Fetal Neonatal Med. 2022 Dec; 35(26):10506-10513. PubMed
  • Schmidt CN, Friedman AM, DiMango EA, Linder AH, Sobhani NC, D'Alton ME, Wen T. Trends in and Outcomes of Deliveries Complicated by Cystic Fibrosis. Obstet Gynecol. 2022 11 01; 140(5):861-868. PubMed
  • Bakhtary S, Panchalee T, Crowe EP, Schwab ME, Zakieh A, Josephson CD, Sobhani NC, Gonzalez-Velez JM, Goel R. Survey of intrauterine red blood cell (RBC) transfusion practices in the United States. Transfusion. 2022 12; 62(12):2449-2453. PubMed
  • Gilner J, Kansal N, Biggio JR, Delaney S, Grotegut CA, Hardy E, Hirshberg A, Kachikis A, LaCourse SM, Martin J, Metz TD, Miller ES, Norton ME, Sinkey R, Sobhani NC, Son SL, Srinivas S, Tita A, Werner EF, Hughes BL. Universal Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Testing for Obstetric Inpatient Units Across the United States. Clin Infect Dis. 2022 08 24; 75(1):e322-e328. PubMed
  • Sobhani NC, Zakieh A, Bakhtary S, Gonzalez JM. Intrauterine transfusion practice patterns in the United States. Am J Obstet Gynecol MFM. 2022 07; 4(4):100655. PubMed
  • Sobhani NC, Mernoff R, Abraha M, Okorie CN, Marquez-Magana L, Gaw SL, Robinson JF. Integrated analysis of transcriptomic datasets to identify placental biomarkers of spontaneous preterm birth. Placenta. 2022 05; 122:66-73. PubMed
  • Wen T, Schmidt CN, Sobhani NC, Guglielminotti J, Miller EC, Sutton D, Lahtermaher Y, D'Alton ME, Friedman AM. Trends and outcomes for deliveries with hypertensive disorders of pregnancy from 2000 to 2018: A repeated cross-sectional study. BJOG. 2022 06; 129(7):1050-1060. PubMed
  • Mok T, Pereira JP, Sobhani NC, Cardozo RF, Valle HA, Dutra BRT, Gama HD, Moreira ME, Vasconcelos Z, Pone M, Gaw SL. Middle Cerebral Artery Dopplers and Abnormal Neonatal Outcomes among Pregnant Women with Zika Virus Infection. Am J Perinatol. 2022 04; 39(6):577-583. PubMed
  • Wen T, Arditi B, Riley LE, Sobhani NC, Norton M, D'Alton M, Friedman AM, Venkatesh KK. Influenza Complicating Delivery Hospitalization and Its Association With Severe Maternal Morbidity in the United States, 2000-2018. Obstet Gynecol. 2021 08 01; 138(2):218-227. PubMed
  • Arditi B, Wen T, Riley LE, D'Alton M, Sobhani NC, Friedman AM, Venkatesh KK. Associations of influenza, chronic comorbid conditions, and severe maternal morbidity among pregnant women in the United States with influenza at delivery hospitalization, 2000-2015. Am J Obstet Gynecol MFM. 2021 11; 3(6):100445. PubMed
  • Sobhani NC, Sparks TN, Gosnell KA, Rand L, Gonzalez JM, Feldstein VA. Outcomes of Monochorionic, Diamniotic Twin Pregnancies with Prenatally Diagnosed Intertwin Weight Discordance. Am J Perinatol. 2021 06; 38(7):649-656. PubMed
  • Zakama A, Sobhani NC, Lamar R, Rosenstein MG. Implementation of Evidence-Based Cervical Ripening Protocol: Outcomes and Next Steps. AJP Rep. 2020 Oct; 10(4):e408-e412. PubMed
  • Compadre AJ, Kohi M, Lokken RP, Blissett S, Harris IS, Lucero J, Rosenstein MG, Sobhani NC. Catheter-Directed Thrombolysis for Submassive Pulmonary Embolism in the Third Trimester of Pregnancy. JACC Case Rep. 2020 Oct; 2(12):1899-1904. PubMed
  • Sobhani NC, Cassidy AG, Qi Z, Yu J, Chetty S, Norton ME. Gross morphologic appearance of chorionic villi and the risk of chromosomal abnormalities. Reprod Sci. 2021 02; 28(2):570-574. PubMed
  • Sobhani NC, Avvad-Portari E, Nascimento ACM, Machado HN, Lobato DSS, Pereira JP, Esquivel MS, Vasconcelos ZC, Zin AA, Tsui I, Adachi K, Brickley EB, Fisher SJ, Nielsen-Saines K, Brasil P, Moreira ME, Gaw SL. Discordant Zika Virus Findings in Twin Pregnancies Complicated by Antenatal Zika Virus Exposure: A Prospective Cohort. J Infect Dis. 2020 05 11; 221(11):1838-1845. PubMed
  • Sobhani NC, Shulman R, Tran EE, Gonzalez JM. Early Onset Severe Hypertensive Disease in Pregnancy and Screening for Antiphospholipid Syndrome. AJP Rep. 2020 Jan; 10(1):e32-e36. PubMed
  • Sobhani NC, Cassidy AG, Zlatnik MG, Rosenstein MG. Prolonged second stage of labor and risk of subsequent spontaneous preterm birth. Am J Obstet Gynecol MFM. 2020 05; 2(2):100093. PubMed
  • Xu Y, Nedungadi TP, Zhu L, Sobhani N, Irani BG, Davis KE, Zhang X, Zou F, Gent LM, Hahner LD, Khan SA, Elias CF, Elmquist JK, Clegg DJ. Distinct Hypothalamic Neurons Mediate Estrogenic Effects on Energy Homeostasis and Reproduction. Cell Metab. 2019 May 07; 29(5):1232. PubMed
  • Sobhani NC, Schultz H, Kheiwa A, Killion M, Parikh NI, Harris IS, Gonzalez JM, Agarwal A. Contraceptive Choices in the Immediate Postpartum Period in Women With Cardiac Disease. Am J Cardiol. 2019 04 15; 123(8):1364-1369. PubMed
  • Sobhani NC, Fay EE, Schiff MA, Stephenson-Famy A, Debiec KE. Randomized Trial of Smartphone-Based Evaluation for an Obstetrics and Gynecology Clerkship. J Surg Educ. 2018 Jul - Aug; 75(4):1006-1013. PubMed
  • Xu Y, Nedungadi TP, Zhu L, Sobhani N, Irani BG, Davis KE, Zhang X, Zou F, Gent LM, Hahner LD, Khan SA, Elias CF, Elmquist JK, Clegg DJ. Distinct hypothalamic neurons mediate estrogenic effects on energy homeostasis and reproduction. Cell Metab. 2011 Oct 05; 14(4):453-65. PubMed
  • Barson JR, Carr AJ, Soun JE, Sobhani NC, Rada P, Leibowitz SF, Hoebel BG. Opioids in the hypothalamic paraventricular nucleus stimulate ethanol intake. Alcohol Clin Exp Res. 2010 Feb; 34(2):214-22. PubMed
  • Barson JR, Carr AJ, Soun JE, Sobhani NC, Leibowitz SF, Hoebel BG. Opioids in the nucleus accumbens stimulate ethanol intake. Physiol Behav. 2009 Oct 19; 98(4):453-9. PubMed
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