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Hythem Nawaytou

MD

  • Associate Professor
  • Pediatric Cardiologist

Biography

Dr. Hythem Nawaytou is a cardiologist who cares for children with pulmonary hypertension in the hospital as well as the clinic. He performs and interprets all types of echocardiography (ultrasound of the heart), including fetal echocardiograms (used to help diagnose and evaluate many heart conditions before birth). Nawaytou's research focuses on ways to better diagnose children with pulmonary hypertension and follow their progress over time. He also studies the use of echocardiography to evaluate heart function. Nawaytou earned combined bachelor of medicine and bachelor of surgery degrees at Cairo University's Kasr Alainy Faculty of Medicine. He completed a residency in pediatrics at State University of New York Downstate Health Sciences University, followed by a fellowship in pediatric cardiology at UCSF and a fellowship in advanced cardiac imaging at Children's Hospital of Philadelphia. In his free time, Nawaytou enjoys painting.

Education & Training

  • Children's Hospital of Philadelphia Advanced Cardiac Imaging
  • UCSF Pediatric Cardiology
  • SUNY Downstate Health Sciences University Pediatrics
  • Kasr Alainy Faculty of Medicine

Clinical Trials

Publications

  • Tsoi SM, Steurer M, Nawaytou H, Cheung S, Keller RL, Fineman JR. Defining the Typical Course of Persistent Pulmonary Hypertension of the Newborn: When to Think Beyond Reversible Causes. J Pediatr. 2024 Oct; 273:114131. PubMed
  • Nawaytou H, Lakkaraju R, Stevens L, Reddy VM, Swami N, Keller RL, Teitel DF, Fineman JR. Management of pulmonary vascular disease associated with congenital left-to-right shunts: A single-center experience. J Thorac Cardiovasc Surg. 2025 Jan; 169(1):231-241.e2. PubMed
  • Nawaytou HM, Mertens LL. Noninvasive Assessment of Myocardial Work in Children. J Am Soc Echocardiogr. 2024 Sep; 37(9):910-913. PubMed
  • Morell E, Colglazier E, Becerra J, Stevens L, Steurer MA, Sharma A, Nguyen H, Kathiriya IS, Weston S, Teitel D, Keller R, Amin EK, Nawaytou H, Fineman JR. A single institution anesthetic experience with catheterization of pediatric pulmonary hypertension patients. Pulm Circ. 2024 Apr; 14(2):e12360. PubMed
  • Tsoi SM, Nawaytou H, Almeneisi H, Steurer M, Zhao Y, Fineman JR, Keller RL. Prostaglandin-E1 infusion in persistent pulmonary hypertension of the newborn. Pediatr Pulmonol. 2024 Feb; 59(2):379-388. PubMed
  • Zach Hutchinson, Michael Smith, Elizabeth Colglazier, Matt Zinter, Christopher Dvorak, Hythem Nawaytou. Abstract 16432: Screening for Cardiovascular Complications in Pediatric Hematopoietic Stem Cell Transplant Patients. Circulation. 2023 Nov 7; 148(Suppl_1).
  • Colglazier E, Ng AJ, Parker C, Woolsey D, Holmes R, Dsouza A, Becerra J, Stevens L, Nawaytou H, Keller RL, Fineman JR. Safety and tolerability of continuous inhaled iloprost in critically ill pediatric pulmonary hypertension patients: A retrospective case series. Pulm Circ. 2023 Jul; 13(3):e12289. PubMed
  • Mahendra M, Chu P, Amin EK, Nawaytou H, Duncan JR, Fineman JR, Smith-Bindman R. Associated radiation exposure from medical imaging and excess lifetime risk of developing cancer in pediatric patients with pulmonary hypertension. Pulm Circ. 2023 Jul; 13(3):e12282. PubMed
  • Hiremath G, Batlivala S, Callahan R, Thatte N, Rockefeller T, Nawaytou H, Reddy SV, Hussain T, Chabiniok R, Butts R, Vettukattil J, Aregullin EO, Aldweib N, Burkhoff D, Brener MI. Clinical Applications of Pressure-Volume Assessment in Congenital Heart Disease. J Soc Cardiovasc Angiogr Interv. 2023 May-Jun; 2(3):100599. PubMed
  • Nawaytou H, Hills NK, Clyman RI. Patent ductus arteriosus and the risk of bronchopulmonary dysplasia-associated pulmonary hypertension. Pediatr Res. 2023 08; 94(2):547-554. PubMed
  • Jain S, Spadafora R, Maxwell S, Botas C, Nawaytou H, von Scheven E, Crouch EE. A Case of Neonatal Lupus Presenting with Myocardial Dysfunction in the Absence of Congenital Heart Block (CHB): Clinical Management and Brief Literature Review of Neonatal Cardiac Lupus. Pediatr Cardiol. 2023 Mar; 44(3):736-739. PubMed
  • Colglazier E, Stevens L, Parker C, Nawaytou HM, Amin EK, Becerra J, Steurer M, Fineman JR. Hemodynamic assessment of transitioning from parenteral prostacyclin to selexipag in pediatric pulmonary hypertension. Pulm Circ. 2022 Oct; 12(4):e12159. PubMed
  • Nawaytou H, Springston C, Lazar A, Keller S, Hogan W, Cresalia N, Peyvandi S, Cocalis M, Moon-Grady A, Brook M. A Measurement-Based Protocol Improves Interrater Agreement and Accuracy of Right Ventricular Systolic Pressure Assessment by Echocardiography in Children: A Call for Quality Improvement. J Am Soc Echocardiogr. 2022 10; 35(10):1091-1100. PubMed
  • Tsoi SM, Jones K, Colglazier E, Parker C, Nawaytou H, Teitel D, Fineman JR, Keller RL. Persistence of persistent pulmonary hypertension of the newborn: A case of de novo TBX4 variant. Pulm Circ. 2022 Jul; 12(3):e12108. PubMed
  • Tai C, Hsieh A, Moon-Grady AJ, Keller RL, Teitel D, Nawaytou HM. Pulmonary artery acceleration time in young children is determined by heart rate and transpulmonary gradient but not by pulmonary blood flow: A simultaneous echocardiography-cardiac catheterization study. Echocardiography. 2022 07; 39(7):895-905. PubMed
  • Stevens L, Colglazier E, Parker C, Amin EK, Nawaytou H, Teitel D, Reddy VM, Welch CL, Chung WK, Fineman JR. Genetics dictating therapeutic decisions in pediatric pulmonary hypertension? A case report suggesting we are getting closer. Pulm Circ. 2022 Jan; 12(1):e12033. PubMed
  • Lin Y, Amin EK, Keller RL, Teitel DF, Nawaytou HM. Doppler Echocardiographic Features of Pulmonary Vein Stenosis in Ex-Preterm Children. J Am Soc Echocardiogr. 2022 04; 35(4):435-442. PubMed
  • Colglazier E, Ng AJ, Parker C, Nawaytou H, Fineman JR. Safety and Tolerability of a Rapid Transition From Intravenous Treprostinil to Oral Selexipag in Three Adolescent Patients With Pulmonary Arterial Hypertension. J Pediatr Pharmacol Ther. 2021; 26(5):512-516. PubMed
  • Hogan WJ, Moon-Grady AJ, Zhao Y, Cresalia NM, Nawaytou H, Quezada E, Brook M, McQuillen P, Peyvandi S. Fetal cerebrovascular response to maternal hyperoxygenation in congenital heart disease: effect of cardiac physiology. Ultrasound Obstet Gynecol. 2021 05; 57(5):769-775. PubMed
  • Nawaytou H, Fineman JR, Moledina S, Ivy D, Abman SH, Cerro MJD. Practice patterns of pulmonary hypertension secondary to left heart disease among pediatric pulmonary hypertension providers. Pulm Circ. 2021 Jan-Mar; 11(1):2045894021991446. PubMed
  • Kramer KP, Chetty SP, Nawaytou H, Vu L, Rogers EE. Fetal Sacrococcygeal Teratoma and the Development of Hydrops. Neoreviews. 2021 02; 22(2):e141-e147. PubMed
  • Amin EK, Austin ED, Parker C, Colglazier E, Nawaytou H, Leary PJ, Hemnes AR, Teitel D, Fineman JR. Novel Documentation of Onset and Rapid Advancement of Pulmonary Arterial Hypertension without Symptoms in BMPR2 Mutation Carriers: Cautionary Tales? Am J Respir Crit Care Med. 2020 12 01; 202(11):1587-1589. PubMed
  • Guslits E, Steurer MA, Nawaytou H, Keller RL. Reply. J Pediatr. 2021 02; 229:312-313. PubMed
  • Guslits E, Steurer MA, Nawaytou H, Keller RL. Longitudinal B-Type Natriuretic Peptide Levels Predict Outcome in Infants with Congenital Diaphragmatic Hernia. J Pediatr. 2021 02; 229:191-198.e2. PubMed
  • Nawaytou H, Steurer MA, Zhao Y, Guslits E, Teitel D, Fineman JR, Keller RL. Clinical Utility of Echocardiography in Former Preterm Infants with Bronchopulmonary Dysplasia. J Am Soc Echocardiogr. 2020 03; 33(3):378-388.e1. PubMed
  • Levy PT, Jain A, Nawaytou H, Teitel D, Keller R, Fineman J, Steinhorn R, Abman SH, McNamara PJ, Pediatric Pulmonary Hypertension Network (PPHNet). Risk Assessment and Monitoring of Chronic Pulmonary Hypertension in Premature Infants. J Pediatr. 2020 02; 217:199-209.e4. PubMed
  • Steurer MA, Nawaytou H, Guslits E, Colglazier E, Teitel D, Fineman JR, Keller RL. Mortality in infants with bronchopulmonary dysplasia: Data from cardiac catheterization. Pediatr Pulmonol. 2019 06; 54(6):804-813. PubMed
  • Yubbu P, Nawaytou HM, Calderon-Anyosa R, Banerjee A. Diagnostic value of myocardial deformation pattern in children with noncompaction cardiomyopathy. Int J Cardiovasc Imaging. 2018 Oct; 34(10):1529-1539. PubMed
  • Nawaytou HM, Montero AE, Yubbu P, Calderón-Anyosa RJC, Sato T, O'Connor MJ, Miller KD, Ursell PC, Hoffman JIE, Banerjee A. A Preliminary Study of Left Ventricular Rotational Mechanics in Children with Noncompaction Cardiomyopathy: Do They Influence Ventricular Function? J Am Soc Echocardiogr. 2018 08; 31(8):951-961. PubMed
  • Nawaytou HM, Mercer-Rosa L, Channing A, Cohen MS. Intraoperative transesophageal echocardiographic predictors of recurrent left ventricular outflow tract obstruction in children undergoing subaortic stenosis resection. Echocardiography. 2018 05; 35(5):678-684. PubMed
  • Hassan F, Patel A, Reddy VM, Nawaytou H. Postablation Right Atrial Dissection in Ebstein's Anomaly. CASE (Phila). 2018 Feb; 2(1):16-19. PubMed
  • Zinter MS, Melton A, Sabnis AJ, Dvorak CC, Elicker BM, Nawaytou HM, Kameny RJ, Fineman JR. Pulmonary veno-occlusive disease in a pediatric hematopoietic stem cell transplant patient: a cautionary tale. Leuk Lymphoma. 2018 06; 59(6):1494-1497. PubMed
  • Kameny RJ, Colglazier E, Nawaytou H, Moore P, Reddy VM, Teitel D, Fineman JR. Pushing the envelope: a treat and repair strategy for patients with advanced pulmonary hypertension associated with congenital heart disease. Pulm Circ. 2017 Jul-Sep; 7(3):747-751. PubMed
  • Putri Yubbu, Andrea Montero, Hythem Nawaytou, Anirban Banerjee. ASSESSMENT OF LEFT VENTRICULAR STRAIN AND ITS CLINICAL CORRELATIONS IN ISOLATED LEFT VENTRICULAR NON-COMPACTION. Journal of the American College of Cardiology. 2017 Mar 1; 69(11):2094.
  • Nawaytou HM, Yubbu P, Montero AE, Nandi D, O'Connor MJ, Shaddy RE, Banerjee A. Left Ventricular Rotational Mechanics in Children After Heart Transplantation. Circ Cardiovasc Imaging. 2016 09; 9(9). PubMed
  • Hythem Nawaytou, Putri Yubbu, Kelley Miller, Anirban Banerjee. Abstract 18230: Wringing Pump or Roller Pump? Insights From Rotational Mechanics in Children With Left Ventricular Noncompaction Cardiomyopathy. Circulation. 2015 Nov 10; 132(suppl_3).
  • Nawaytou HM, Peyvandi S, Brook MM, Silverman N, Moon-Grady AJ. Right Ventricular Systolic-to-Diastolic Time Index: Hypoplastic Left Heart Fetuses Differ Significantly from Normal Fetuses. J Am Soc Echocardiogr. 2016 Feb; 29(2):143-9. PubMed
  • Harold Bernstein, Hythem Nawaytou. Biomarkers of cardiac function and outcome in univentricular congenital heart disease. Current Biomarker Findings. 2014 Jun 1; Volume 4:53-59.
  • Nawaytou H, Bernstein HS. Biomarkers in pediatric heart disease. Biomark Med. 2014; 8(7):943-63. PubMed
View Hythem Nawaytou, MD's research profile on UCSF Profiles
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