Immune System Drives Pregnancy Complications after Fetal Surgery in Mice

Dr Tippi MacKenzie

MacKenzie and her UCSF colleagues have shown that, in mice at least, pregnancy complications after fetal surgery are triggered by activation of the mother’s T cells – the same T cells that cause the body to reject a donor organ after transplant surgery. “We have the ability to design specific medical treatments to prevent it – for example, by using medications that target some of the pathways involved in T cell-mediated rejection."

Immune System Drives Pregnancy Complications after Fetal Surgery in Mice — UCSF News