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Roberta L. Keller

MD

  • Professor, Pediatrics
  • Medical Director, Neonatal ECMO Program

Biography

Dr. Keller received her medical degree from the University of California San Francisco, where she also undertook her postgraduate training, completing a residency in Pediatrics and a fellowship in Neonatal-Perinatal Medicine at the UCSF Medical Center/UCSF Children’s Hospital. During her fellowship, she was the recipient of the Glaser Pediatric Research Network fellowship. She is the director of the UCSF Extracoporeal Membrane Oxygenation (ECMO) program for newborns and the coordinator of the UCSF Neonatology Clinical Consensus program. She joined the pediatrics faculty in 2003.

Education & Training

  • University of California, San Francisco, CA Diversity, Equity, and Inclusion Champion Training
  • UCSF Cardiovascular Research Institute Neonatal-Perinatal Medicine
  • University of California, San Francisco Neonatal-Perinatal Medicince
  • University of California, San Francisco School of Medicine
  • University of California, San Francisco Medicine

Research Activities & Funding

  • Clinical and Translational Science Institute (CTSI)

    —

    Sponsor: NIH/NCATS UL2 TR001872

    Role: Co-Investigator, Integrating Special Populations Core/Member, Strategic Advisory Board

  • The Urinary Metabolome and bronchopulmonary dysplasia in premature infants

    —

    Sponsor: NIH/NICHD R21 HD097600

    Role: Co-Investigator

  • COVID-19: PRIORITY Registry

    —

    Sponsor: Bill and Melinda Gates Foundation

    Role: Co-Investigator

  • Developmental Impact of NICU Exposures (DINE)

    —

    Sponsor: NIH Office of the Director UG3 OD023320

    Role: Co-Investigator, Site PI, Cohort PI

  • UCSF Clinical Research Center for Prematurity and Respiratory Outcomes Program

    —

    Sponsor: NIH U01HL101798

    Role: Principal Investigator

  • Trial of Late Surfactant (TOLSURF) to prevent Bronchopulmonary Dysplasia (BPD)

    —

    Sponsor: NIH/NHLBI U01 HL094338

    Role: Co-Investigator

  • Chronic Sildenafil for Severe Diaphragmatic Hernia

    —

    Sponsor: NIH K23HL079922

    Role: Principal Investigator

Publications

  • Sharma M, Fineman DC, Keller RL, Maltepe E, Rinaudo PF, Steurer MA. The effect of fertility treatment and socioeconomic status on neonatal and post-neonatal mortality in the United States. J Perinatol. 2024 Feb; 44(2):187-194. PubMed
  • Tsoi SM, Nawaytou H, Almeneisi H, Steurer M, Zhao Y, Fineman JR, Keller RL. Prostaglandin-E1 infusion in persistent pulmonary hypertension of the newborn. Pediatr Pulmonol. 2024 Feb; 59(2):379-388. PubMed
  • Moore SS, Keller RL, Altit G. Congenital Diaphragmatic Hernia: Pulmonary Hypertension and Pulmonary Vascular Disease. Clin Perinatol. 2024 Mar; 51(1):151-170. PubMed
  • Colglazier E, Ng AJ, Parker C, Woolsey D, Holmes R, Dsouza A, Becerra J, Stevens L, Nawaytou H, Keller RL, Fineman JR. Safety and tolerability of continuous inhaled iloprost in critically ill pediatric pulmonary hypertension patients: A retrospective case series. Pulm Circ. 2023 Jul; 13(3):e12289. PubMed
  • Fineman DC, Keller RL, Maltepe E, Rinaudo PF, Steurer MA. Fertility treatment increases the risk of preterm birth independent of multiple gestations. F S Rep. 2023 Sep; 4(3):313-320. PubMed
  • Smith MA, Steurer MA, Mahendra M, Zinter MS, Keller RL. Sociodemographic factors associated with tracheostomy and mortality in bronchopulmonary dysplasia. Pediatr Pulmonol. 2023 04; 58(4):1237-1246. PubMed
  • Moon-Grady AJ, Byrne FA, Lusk LA, Keller RL. Expected small left heart size in the presence of congenital diaphragmatic hernia: Fetal values and Z-scores for infants confirmed to have no heart disease postnatally. Front Pediatr. 2022; 10:1083370. PubMed
  • Tsoi SM, Jones K, Colglazier E, Parker C, Nawaytou H, Teitel D, Fineman JR, Keller RL. Persistence of persistent pulmonary hypertension of the newborn: A case of de novo TBX4 variant. Pulm Circ. 2022 Jul; 12(3):e12108. PubMed
  • Tai C, Hsieh A, Moon-Grady AJ, Keller RL, Teitel D, Nawaytou HM. Pulmonary artery acceleration time in young children is determined by heart rate and transpulmonary gradient but not by pulmonary blood flow: A simultaneous echocardiography-cardiac catheterization study. Echocardiography. 2022 07; 39(7):895-905. PubMed
  • Schwab ME, Crennan M, Burke S, Sang H, Klarich MK, Keller RL, Vu LT. Oral Feeding in Infants After Congenital Diaphragmatic Hernia Repair While on Non-invasive Positive Pressure Ventilation: The Impact of a Dysphagia Provider-Led Protocol. Dysphagia. 2022 10; 37(5):1305-1313. PubMed
  • Lin Y, Amin EK, Keller RL, Teitel DF, Nawaytou HM. Doppler Echocardiographic Features of Pulmonary Vein Stenosis in Ex-Preterm Children. J Am Soc Echocardiogr. 2022 04; 35(4):435-442. PubMed
  • Abman SH, Mullen MP, Sleeper LA, Austin ED, Rosenzweig EB, Kinsella JP, Ivy D, Hopper RK, Raj JU, Fineman J, Keller RL, Bates A, Krishnan US, Avitabile CM, Davidson A, Natter MD, Mandl KD, Pediatric Pulmonary Hypertension Network. Characterisation of paediatric pulmonary hypertensive vascular disease from the PPHNet Registry. Eur Respir J. 2022 01; 59(1). PubMed
  • MacKenzie TC, Amid A, Angastiniotis M, Butler C, Gilbert S, Gonzalez J, Keller RL, Kharbanda S, Kirby-Allen M, Koenig BA, Kyono W, Lal A, Lianoglou BR, Norton ME, Ogasawara KK, Panchalee T, Rosner M, Schwab M, Thompson A, Waye JS, Vichinsky E. Consensus statement for the perinatal management of patients with α thalassemia major. Blood Adv. 2021 12 28; 5(24):5636-5639. PubMed
  • Flaherman VJ, Afshar Y, Boscardin WJ, Keller RL, H Mardy A, Prahl MK, T Phillips C, Asiodu IV, Berghella V, Chambers BD, Crear-Perry J, Jamieson DJ, Jacoby VL, Gaw SL. Infant Outcomes Following Maternal Infection With Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2): First Report From the Pregnancy Coronavirus Outcomes Registry (PRIORITY) Study. Clin Infect Dis. 2021 11 02; 73(9):e2810-e2813. PubMed
  • Rios DR, Lapointe A, Schmolzer GM, Mohammad K, VanMeurs KP, Keller RL, Sehgal A, Lakshminrusimha S, Giesinger RE, Newborn Brain Society Guidelines and Publications Committee. Hemodynamic optimization for neonates with neonatal encephalopathy caused by a hypoxic ischemic event: Physiological and therapeutic considerations. Semin Fetal Neonatal Med. 2021 08; 26(4):101277. PubMed
  • Fineman DC, Keller RL, Maltepe E, Rinaudo PF, Steurer MA. Outcomes of Very Preterm Infants Conceived with Assisted Reproductive Technologies. J Pediatr. 2021 Sep; 236:47-53.e1. PubMed
  • Kosiv KA, Moon-Grady A, Hogan W, Keller R, Rapoport R, Rogers E, Feldstein VA, Lee H, Peyvandi S. Fetal cerebrovascular impedance is reduced in left congenital diaphragmatic hernia. Ultrasound Obstet Gynecol. 2021 03; 57(3):386-391. PubMed
  • Varghese NP, Tillman RH, Keller RL. Pulmonary hypertension is an important co-morbidity in developmental lung diseases of infancy: Bronchopulmonary dysplasia and congenital diaphragmatic hernia. Pediatr Pulmonol. 2021 03; 56(3):670-677. PubMed
  • Strobel KM, Romero T, Kramer K, Fernandez E, Rottkamp C, Uy C, Keller R, Moyer L, Poulain F, Kim JH, DeUgarte DA, Calkins KL, University of California Fetal Consortium. Growth Failure Prevalence in Neonates with Gastroschisis : A Statewide Cohort Study. J Pediatr. 2021 06; 233:112-118.e3. PubMed
  • Steurer MA, Peyvandi S, Costello JM, Moon-Grady AJ, Habib RH, Hill KD, Jacobs ML, Jelliffe-Pawlowski LL, Keller RL, Pasquali SK, Reddy VM, Tabbutt S, Rajagopal S. Association between Z-score for birth weight and postoperative outcomes in neonates and infants with congenital heart disease. J Thorac Cardiovasc Surg. 2021 12; 162(6):1838-1847.e4. PubMed
  • Guslits E, Steurer MA, Nawaytou H, Keller RL. Reply. J Pediatr. 2021 02; 229:312-313. PubMed
  • Guslits E, Steurer MA, Nawaytou H, Keller RL. Longitudinal B-Type Natriuretic Peptide Levels Predict Outcome in Infants with Congenital Diaphragmatic Hernia. J Pediatr. 2021 02; 229:191-198.e2. PubMed
  • Grelli KN, Keller RL, Rogers EE, Partridge JC, Xu D, Barkovich AJ, Gano D. Bronchopulmonary dysplasia precursors influence risk of white matter injury and adverse neurodevelopmental outcome in preterm infants. Pediatr Res. 2021 08; 90(2):359-365. PubMed
  • Rintoul NE, Keller RL, Walsh WF, Burrows PK, Thom EA, Kallan MJ, Howell LJ, Adzick NS, MOMS Investigators. The Management of Myelomeningocele Study: Short-Term Neonatal Outcomes. Fetal Diagn Ther. 2020; 47(12):865-872. PubMed
  • Mahendra M, Steurer-Muller M, Hohmann SF, Keller RL, Aswani A, Dudley RA. Predicting NICU admissions in near-term and term infants with low illness acuity. J Perinatol. 2021 03; 41(3):478-485. PubMed
  • Nawaytou H, Steurer MA, Zhao Y, Guslits E, Teitel D, Fineman JR, Keller RL. Clinical Utility of Echocardiography in Former Preterm Infants with Bronchopulmonary Dysplasia. J Am Soc Echocardiogr. 2020 03; 33(3):378-388.e1. PubMed
  • Greenberg JM, Poindexter BB, Shaw PA, Bellamy SL, Keller RL, Moore PE, McPherson C, Ryan RM. Respiratory medication use in extremely premature (<29 weeks) infants during initial NICU hospitalization: Results from the prematurity and respiratory outcomes program. Pediatr Pulmonol. 2020 02; 55(2):360-368. PubMed
  • Steurer MA, Peyvandi S, Baer RJ, Oltman SP, Chambers CD, Norton ME, Ryckman KK, Moon-Grady AJ, Keller RL, Shiboski SC, Jelliffe-Pawlowski LL. Impaired Fetal Environment and Gestational Age: What Is Driving Mortality in Neonates With Critical Congenital Heart Disease? J Am Heart Assoc. 2019 11 19; 8(22):e013194. PubMed
  • Levy PT, Jain A, Nawaytou H, Teitel D, Keller R, Fineman J, Steinhorn R, Abman SH, McNamara PJ, Pediatric Pulmonary Hypertension Network (PPHNet). Risk Assessment and Monitoring of Chronic Pulmonary Hypertension in Premature Infants. J Pediatr. 2020 02; 217:199-209.e4. PubMed
  • Steurer MA, Baer RJ, Oltman S, Ryckman KK, Feuer SK, Rogers E, Keller RL, Jelliffe-Pawlowski LL. Morbidity of Persistent Pulmonary Hypertension of the Newborn in the First Year of Life. J Pediatr. 2019 10; 213:58-65.e4. PubMed
  • Levy PT, Keller RL. Pulmonary Vascular Disease in Premature Infants. Early Predictive Models of Late Respiratory Morbidity. Am J Respir Crit Care Med. 2019 Apr 15; 199(8):943-944. PubMed
  • Steurer MA, Nawaytou H, Guslits E, Colglazier E, Teitel D, Fineman JR, Keller RL. Mortality in infants with bronchopulmonary dysplasia: Data from cardiac catheterization. Pediatr Pulmonol. 2019 06; 54(6):804-813. PubMed
  • Ryan RM, Keller RL, Poindexter BB, D'Angio CT, Shaw PA, Bellamy SL, Moore PE, McPherson C, Greenberg JM, PROP Investigators. Respiratory Medications in Infants <29 Weeks during the First Year Postdischarge: The Prematurity and Respiratory Outcomes Program (PROP) Consortium. J Pediatr. 2019 05; 208:148-155.e3. PubMed
  • Taglauer E, Abman SH, Keller RL. Recent advances in antenatal factors predisposing to bronchopulmonary dysplasia. Semin Perinatol. 2018 11; 42(7):413-424. PubMed
  • Steurer MA, Baer RJ, Burke E, Peyvandi S, Oltman S, Chambers CD, Norton ME, Rand L, Rajagopal S, Ryckman KK, Feuer SK, Liang L, Paynter RA, McCarthy M, Moon-Grady AJ, Keller RL, Jelliffe-Pawlowski LL. Effect of Fetal Growth on 1-Year Mortality in Neonates With Critical Congenital Heart Disease. J Am Heart Assoc. 2018 09 04; 7(17):e009693. PubMed
  • Torgerson DG, Ballard PL, Keller RL, Oh SS, Huntsman S, Hu D, Eng C, Burchard EG, Ballard RA, TOLSURF Study Group. Ancestry and genetic associations with bronchopulmonary dysplasia in preterm infants. Am J Physiol Lung Cell Mol Physiol. 2018 11 01; 315(5):L858-L869. PubMed
  • Ballard PL, Keller RL, Truog WE, Chapin C, Horneman H, Segal MR, Ballard RA, Tolsurf Investigators. Surfactant status and respiratory outcome in premature infants receiving late surfactant treatment. Pediatr Res. 2019 02; 85(3):305-311. PubMed
  • Balkin EM, Zinter MS, Rajagopal SK, Keller RL, Fineman JR, Steurer MA. Intensive Care Mortality Prognostic Model for Pediatric Pulmonary Hypertension. Pediatr Crit Care Med. 2018 08; 19(8):733-740. PubMed
  • Ballard RA, Ballard PL, Askie LM, Schreiber MD, Hibbs AM, Torgerson DG, Keller RL. Reply. J Pediatr. 2018 10; 201:300-301. PubMed
  • Steurer MA, Oltman S, Baer RJ, Feuer S, Liang L, Paynter RA, Rand L, Ryckman KK, Keller RL, Jelliffe-Pawlowski LL. Altered metabolites in newborns with persistent pulmonary hypertension. Pediatr Res. 2018 08; 84(2):272-278. PubMed
  • Kinsella JP, Steinhorn RH, Mullen MP, Hopper RK, Keller RL, Ivy DD, Austin ED, Krishnan US, Rosenzweig EB, Fineman JR, Everett AD, Hanna BD, Humpl T, Raj JU, Abman SH, Pediatric Pulmonary Hypertension Network (PPHNet). The Left Ventricle in Congenital Diaphragmatic Hernia: Implications for the Management of Pulmonary Hypertension. J Pediatr. 2018 06; 197:17-22. PubMed
  • Wai KC, Hibbs AM, Steurer MA, Black DM, Asselin JM, Eichenwald EC, Ballard PL, Ballard RA, Keller RL, Trial of Late Surfactant (TOLSURF) Study Group. Maternal Black Race and Persistent Wheezing Illness in Former Extremely Low Gestational Age Newborns: Secondary Analysis of a Randomized Trial. J Pediatr. 2018 07; 198:201-208.e3. PubMed
  • Sperling JD, Sparks TN, Berger VK, Farrell JA, Gosnell K, Keller RL, Norton ME, Gonzalez JM. Prenatal Diagnosis of Congenital Diaphragmatic Hernia: Does Laterality Predict Perinatal Outcomes? Am J Perinatol. 2018 08; 35(10):919-924. PubMed
  • Balkin EM, Steurer MA, Delagnes EA, Zinter MS, Rajagopal S, Keller RL, Fineman JR. Multicenter mortality and morbidity associated with pulmonary hypertension in the pediatric intensive care unit. Pulm Circ. 2018 Jan-Mar; 8(1):2045893217745785. PubMed
  • Black SM, Field-Ridley A, Sharma S, Kumar S, Keller RL, Kameny R, Maltepe E, Datar SA, Fineman JR. Altered Carnitine Homeostasis in Children With Increased Pulmonary Blood Flow Due to Ventricular Septal Defects. Pediatr Crit Care Med. 2017 Oct; 18(10):931-934. PubMed
  • Steurer MA, Baer RJ, Keller RL, Oltman S, Chambers CD, Norton ME, Peyvandi S, Rand L, Rajagopal S, Ryckman KK, Moon-Grady AJ, Jelliffe-Pawlowski LL. Gestational Age and Outcomes in Critical Congenital Heart Disease. Pediatrics. 2017 Oct; 140(4). PubMed
  • Krishnan U, Feinstein JA, Adatia I, Austin ED, Mullen MP, Hopper RK, Hanna B, Romer L, Keller RL, Fineman J, Steinhorn R, Kinsella JP, Ivy DD, Rosenzweig EB, Raj U, Humpl T, Abman SH, Pediatric Pulmonary Hypertension Network (PPHNet). Evaluation and Management of Pulmonary Hypertension in Children with Bronchopulmonary Dysplasia. J Pediatr. 2017 09; 188:24-34.e1. PubMed
  • Keller RL, Ballard RA. Reply. J Pediatr. 2017 10; 189:241-242. PubMed
  • Keller RL, Feng R, DeMauro SB, Ferkol T, Hardie W, Rogers EE, Stevens TP, Voynow JA, Bellamy SL, Shaw PA, Moore PE, Prematurity and Respiratory Outcomes Program. Bronchopulmonary Dysplasia and Perinatal Characteristics Predict 1-Year Respiratory Outcomes in Newborns Born at Extremely Low Gestational Age: A Prospective Cohort Study. J Pediatr. 2017 08; 187:89-97.e3. PubMed
  • Keller RL, Eichenwald EC, Hibbs AM, Rogers EE, Wai KC, Black DM, Ballard PL, Asselin JM, Truog WE, Merrill JD, Mammel MC, Steinhorn RH, Ryan RM, Durand DJ, Bendel CM, Bendel-Stenzel EM, Courtney SE, Dhanireddy R, Hudak ML, Koch FR, Mayock DE, McKay VJ, Helderman J, Porta NF, Wadhawan R, Palermo L, Ballard RA, TOLSURF Study Group. The Randomized, Controlled Trial of Late Surfactant: Effects on Respiratory Outcomes at 1-Year Corrected Age. J Pediatr. 2017 04; 183:19-25.e2. PubMed
  • Wai KC, Keller RL, Lusk LA, Ballard RA, Chan DK, Trial of Late Surfactant (TOLSURF) Study Group. Characteristics of Extremely Low Gestational Age Newborns Undergoing Tracheotomy: A Secondary Analysis of the Trial of Late Surfactant Randomized Clinical Trial. JAMA Otolaryngol Head Neck Surg. 2017 01 01; 143(1):13-19. PubMed
  • Steurer MA, Jelliffe-Pawlowski LL, Baer RJ, Partridge JC, Rogers EE, Keller RL. Persistent Pulmonary Hypertension of the Newborn in Late Preterm and Term Infants in California. Pediatrics. 2017 01; 139(1). PubMed
  • Basta AM, Lusk LA, Keller RL, Filly RA. Spleen Behind the Heart Complicates Lung-to-Head Ratio Measurement in Left-Sided Congenital Diaphragmatic Hernia. J Ultrasound Med. 2016 Dec; 35(12):2717-2721. PubMed
  • Wai KC, Kohn MA, Ballard RA, Truog WE, Black DM, Asselin JM, Ballard PL, Rogers EE, Keller RL, Trial of Late Surfactant (TOLSURF) Study Group. Early Cumulative Supplemental Oxygen Predicts Bronchopulmonary Dysplasia in High Risk Extremely Low Gestational Age Newborns. J Pediatr. 2016 Oct; 177:97-102.e2. PubMed
  • Keller RL. Pulmonary Hypertension and Pulmonary Vasodilators. Clin Perinatol. 2016 Mar; 43(1):187-202. PubMed
  • Balkin EM, Olson ED, Robertson L, Adatia I, Fineman JR, Keller RL. Change in Pediatric Functional Classification During Treatment and Morbidity and Mortality in Children with Pulmonary Hypertension. Pediatr Cardiol. 2016 Apr; 37(4):756-64. PubMed
  • Derderian SC, Jayme CM, Cheng LS, Keller RL, Moon-Grady AJ, MacKenzie TC. Mass Effect Alone May Not Explain Pulmonary Vascular Pathology in Severe Congenital Diaphragmatic Hernia. Fetal Diagn Ther. 2016; 39(2):117-24. PubMed
  • Kinsella JP, Steinhorn RH, Krishnan US, Feinstein JA, Adatia I, Austin ED, Rosenzweig EB, Everett AD, Fineman JR, Hanna BD, Hopper RK, Humpl T, Ivy DD, Keller RL, Mullen MP, Raj JU, Wessel DL, Abman SH. Recommendations for the Use of Inhaled Nitric Oxide Therapy in Premature Newborns with Severe Pulmonary Hypertension. J Pediatr. 2016 Mar; 170:312-4. PubMed
  • Basta AM, Lusk LA, Keller RL, Filly RA. Fetal Stomach Position Predicts Neonatal Outcomes in Isolated Left-Sided Congenital Diaphragmatic Hernia. Fetal Diagn Ther. 2016; 39(4):248-55. PubMed
  • Byrne FA, Keller RL, Meadows J, Miniati D, Brook MM, Silverman NH, Moon-Grady AJ. Severe left diaphragmatic hernia limits size of fetal left heart more than does right diaphragmatic hernia. Ultrasound Obstet Gynecol. 2015 Dec; 46(6):688-94. PubMed
  • Abman SH, Hansmann G, Archer SL, Ivy DD, Adatia I, Chung WK, Hanna BD, Rosenzweig EB, Raj JU, Cornfield D, Stenmark KR, Steinhorn R, Thébaud B, Fineman JR, Kuehne T, Feinstein JA, Friedberg MK, Earing M, Barst RJ, Keller RL, Kinsella JP, Mullen M, Deterding R, Kulik T, Mallory G, Humpl T, Wessel DL, American Heart Association Council on Cardiopulmonary, Critical Care, Perioperative and Resuscitatio. Pediatric Pulmonary Hypertension: Guidelines From the American Heart Association and American Thoracic Society. Circulation. 2015 Nov 24; 132(21):2037-99. PubMed
  • Ballard RA, Keller RL, Black DM, Ballard PL, Merrill JD, Eichenwald EC, Truog WE, Mammel MC, Steinhorn RH, Rogers EE, Ryan RM, Durand DJ, Asselin JM, Bendel CM, Bendel-Stenzel EM, Courtney SE, Dhanireddy R, Hudak ML, Koch FR, Mayock DE, McKay VJ, O'Shea TM, Porta NF, Wadhawan R, Palermo L, TOLSURF Study Group. Randomized Trial of Late Surfactant Treatment in Ventilated Preterm Infants Receiving Inhaled Nitric Oxide. J Pediatr. 2016 Jan; 168:23-29.e4. PubMed
  • Islam JY, Keller RL, Aschner JL, Hartert TV, Moore PE. Understanding the Short- and Long-Term Respiratory Outcomes of Prematurity and Bronchopulmonary Dysplasia. Am J Respir Crit Care Med. 2015 Jul 15; 192(2):134-56. PubMed
  • Olson E, Lusk LA, Fineman JR, Robertson L, Keller RL. Short-Term Treprostinil Use in Infants with Congenital Diaphragmatic Hernia following Repair. J Pediatr. 2015 Sep; 167(3):762-4. PubMed
  • Lusk LA, Wai KC, Moon-Grady AJ, Basta AM, Filly R, Keller RL. Fetal ultrasound markers of severity predict resolution of pulmonary hypertension in congenital diaphragmatic hernia. Am J Obstet Gynecol. 2015 Aug; 213(2):216.e1-8. PubMed
  • Lusk LA, Wai KC, Moon-Grady AJ, Steurer MA, Keller RL. Persistence of pulmonary hypertension by echocardiography predicts short-term outcomes in congenital diaphragmatic hernia. J Pediatr. 2015 Feb; 166(2):251-6.e1. PubMed
  • Lusk LA, Brown EG, Overcash RT, Grogan TR, Keller RL, Kim JH, Poulain FR, Shew SB, Uy C, DeUgarte DA, University of California Fetal Consortium. Multi-institutional practice patterns and outcomes in uncomplicated gastroschisis: a report from the University of California Fetal Consortium (UCfC). J Pediatr Surg. 2014 Dec; 49(12):1782-6. PubMed
  • Derderian SC, Jeanty C, Fleck SR, Cheng LS, Peyvandi S, Moon-Grady AJ, Farrell J, Hirose S, Gonzalez J, Keller RL, MacKenzie TC. The many faces of hydrops. J Pediatr Surg. 2015 Jan; 50(1):50-4; discussion 54. PubMed
  • Steurer MA, Moon-Grady AJ, Fineman JR, Sun CE, Lusk LA, Wai KC, Keller RL. B-type natriuretic peptide: prognostic marker in congenital diaphragmatic hernia. Pediatr Res. 2014 Dec; 76(6):549-54. PubMed
  • Guay-Woodford LM, Bissler JJ, Braun MC, Bockenhauer D, Cadnapaphornchai MA, Dell KM, Kerecuk L, Liebau MC, Alonso-Peclet MH, Shneider B, Emre S, Heller T, Kamath BM, Murray KF, Moise K, Eichenwald EE, Evans J, Keller RL, Wilkins-Haug L, Bergmann C, Gunay-Aygun M, Hooper SR, Hardy KK, Hartung EA, Streisand R, Perrone R, Moxey-Mims M. Consensus expert recommendations for the diagnosis and management of autosomal recessive polycystic kidney disease: report of an international conference. J Pediatr. 2014 Sep; 165(3):611-7. PubMed
  • Ballard PL, Keller RL, Black DM, Durand DJ, Merrill JD, Eichenwald EC, Truog WE, Mammel MC, Steinhorn R, Ryan RM, Courtney SE, Horneman H, Ballard RA, Investigators of TOLSURF Pilot and TOLSURF. Inhaled nitric oxide increases urinary nitric oxide metabolites and cyclic guanosine monophosphate in premature infants: relationship to pulmonary outcome. Am J Perinatol. 2015 Feb; 32(3):225-32. PubMed
  • Derderian SC, Trivedi S, Farrell J, Keller RL, Rand L, Goldstein R, Feldstein VA, Hirose S, MacKenzie TC. Outcomes of fetal intervention for primary hydrothorax. J Pediatr Surg. 2014 Jun; 49(6):900-3; discussion 903-4. PubMed
  • Rocha LA, Byrne FA, Keller RL, Miniati D, Brook MM, Silverman NH, Moon-Grady AJ. Left heart structures in human neonates with congenital diaphragmatic hernia and the effect of fetal endoscopic tracheal occlusion. Fetal Diagn Ther. 2014; 35(1):36-43. PubMed
  • Keller RL, Steinhorn RH. Extracorporeal membrane oxygenation in resource-limited countries. Pediatr Crit Care Med. 2013 Nov; 14(9):900-2. PubMed
  • Radman M, Keller RL, Oishi P, Datar SA, Wellnitz K, Azakie A, Hanley F, Char D, Hsu JH, Amrinovin R, Adatia I, Fineman JR. Preoperative B-type natriuretic peptide levels are associated with outcome after total cavopulmonary connection (Fontan). J Thorac Cardiovasc Surg. 2014 Jul; 148(1):212-9. PubMed
  • Oishi PE, Klein OD, Keller RL, University of California San Francisco Neonatology and Pediatric Critical Care Early Faculty Develop. Developing physician-scientists in the fields of neonatology and pediatric critical care medicine: an effort to formulate a departmental policy. J Pediatr. 2013 Sep; 163(3):616-7.e1. PubMed
  • Fleck S, Bautista G, Keating SM, Lee TH, Keller RL, Moon-Grady AJ, Gonzales K, Norris PJ, Busch MP, Kim CJ, Romero R, Lee H, Miniati D, MacKenzie TC. Fetal production of growth factors and inflammatory mediators predicts pulmonary hypertension in congenital diaphragmatic hernia. Pediatr Res. 2013 Sep; 74(3):290-8. PubMed
  • Amirnovin R, Oishi P, Fineman JR, Keller RL. Reply to the editor. J Thorac Cardiovasc Surg. 2013 May; 145(5):1416. PubMed
  • Radman M, Mack R, Barnoya J, Castañeda A, Rosales M, Azakie A, Mehta N, Keller R, Datar S, Oishi P, Fineman J. The effect of preoperative nutritional status on postoperative outcomes in children undergoing surgery for congenital heart defects in San Francisco (UCSF) and Guatemala City (UNICAR). J Thorac Cardiovasc Surg. 2014 Jan; 147(1):442-50. PubMed
  • Keller RL, Merrill JD, Black DM, Steinhorn RH, Eichenwald EC, Durand DJ, Ryan RM, Truog WE, Courtney SE, Ballard PL, Ballard RA. Late administration of surfactant replacement therapy increases surfactant protein-B content: a randomized pilot study. Pediatr Res. 2012 Dec; 72(6):613-9. PubMed
  • Field-Ridley A, Heljasvaara R, Pihlajaniemi T, Adatia I, Sun C, Keller RL, Gong WH, Datar S, Oishi P, Fineman JR. Endostatin, an inhibitor of angiogenesis, decreases after bidirectional superior cavopulmonary anastamosis. Pediatr Cardiol. 2013 Feb; 34(2):291-5. PubMed
  • Amirnovin R, Keller RL, Herrera C, Hsu JH, Datar S, Karl TR, Adatia I, Oishi P, Fineman JR. B-type natriuretic peptide levels predict outcomes in infants undergoing cardiac surgery in a lesion-dependent fashion. J Thorac Cardiovasc Surg. 2013 May; 145(5):1279-87. PubMed
  • Oishi PE, Keller RL. When persistent pulmonary hypertension of the newborn persists. Pediatr Crit Care Med. 2012 Mar; 13(2):224-5. PubMed
  • Jancelewicz T, Vu LT, Keller RL, Jelin EB, Bratton BJ, Townsend TC, Nobuhara KK. Outcomes of multigestational pregnancies affected by congenital diaphragmatic hernia. J Pediatr Surg. 2010 Sep; 45(9):1753-8. PubMed
  • Keller RL, Tacy TA, Hendricks-Munoz K, Xu J, Moon-Grady AJ, Neuhaus J, Moore P, Nobuhara KK, Hawgood S, Fineman JR. Congenital diaphragmatic hernia: endothelin-1, pulmonary hypertension, and disease severity. Am J Respir Crit Care Med. 2010 Aug 15; 182(4):555-61. PubMed
  • Walsh MC, Hibbs AM, Martin CR, Cnaan A, Keller RL, Vittinghoff E, Martin RJ, Truog WE, Ballard PL, Zadell A, Wadlinger SR, Coburn CE, Ballard RA, NO CLD Study Group. Two-year neurodevelopmental outcomes of ventilated preterm infants treated with inhaled nitric oxide. J Pediatr. 2010 Apr; 156(4):556-61.e1. PubMed
  • Jancelewicz T, Vu LT, Keller RL, Bratton B, Lee H, Farmer D, Harrison M, Miniati D, Mackenzie T, Hirose S, Nobuhara K. Long-term surgical outcomes in congenital diaphragmatic hernia: observations from a single institution. J Pediatr Surg. 2010 Jan; 45(1):155-60; discussion 160. PubMed
  • Sherlock RL, McQuillen PS, Miller SP, aCCENT. Preventing brain injury in newborns with congenital heart disease: brain imaging and innovative trial designs. Stroke. 2009 Jan; 40(1):327-32. PubMed
  • Grethel EJ, Farrell J, Ball RH, Keller RL, Goldstein RB, Lee H, Farmer DL, Harrison MR, Nobuhara KK. Does congenital diaphragmatic hernia associated with bronchopulmonary sequestration portend a better prognosis? Fetal Diagn Ther. 2008; 23(4):250-3. PubMed
  • Hsu JH, Oishi PE, Keller RL, Chikovani O, Karl TR, Azakie A, Adatia I, Fineman JR. Perioperative B-type natriuretic peptide levels predict outcome after bidirectional cavopulmonary anastomosis and total cavopulmonary connection. J Thorac Cardiovasc Surg. 2008 Apr; 135(4):746-53. PubMed
  • Mirow L, Hauenschild L, Hildebrand P, Kleemann M, Keller R, Franke C, Roblick UJ, Bruch HP, Kujath P. [Recurrence of Crohn's disease after surgery--causes and risks]. Zentralbl Chir. 2008 Apr; 133(2):182-7. PubMed
  • Chikovani O, Hsu JH, Keller R, Karl TR, Azakie A, Adatia I, Oishi P, Fineman JR. B-type natriuretic peptide levels predict outcomes for children on extracorporeal life support after cardiac surgery. J Thorac Cardiovasc Surg. 2007 Nov; 134(5):1179-87. PubMed
  • Hsu JH, Keller RL, Chikovani O, Cheng H, Hollander SA, Karl TR, Azakie A, Adatia I, Oishi P, Fineman JR. B-type natriuretic peptide levels predict outcome after neonatal cardiac surgery. J Thorac Cardiovasc Surg. 2007 Oct; 134(4):939-45. PubMed
  • Jani J, Nicolaides KH, Keller RL, Benachi A, Peralta CF, Favre R, Moreno O, Tibboel D, Lipitz S, Eggink A, Vaast P, Allegaert K, Harrison M, Deprest J, Antenatal-CDH-Registry Group. Observed to expected lung area to head circumference ratio in the prediction of survival in fetuses with isolated diaphragmatic hernia. Ultrasound Obstet Gynecol. 2007 Jul; 30(1):67-71. PubMed
  • Yang SH, Nobuhara KK, Keller RL, Ball RH, Goldstein RB, Feldstein VA, Callen PW, Filly RA, Farmer DL, Harrison MR, Lee H. Reliability of the lung-to-head ratio as a predictor of outcome in fetuses with isolated left congenital diaphragmatic hernia at gestation outside 24-26 weeks. Am J Obstet Gynecol. 2007 Jul; 197(1):30.e1-7. PubMed
  • Keller RL. Antenatal and postnatal lung and vascular anatomic and functional studies in congenital diaphragmatic hernia: implications for clinical management. Am J Med Genet C Semin Med Genet. 2007 May 15; 145C(2):184-200. PubMed
  • Keller RL, Moore P, Teitel D, Hawgood S, McQuitty J, Fineman JR. Abnormal vascular tone in infants and children with lung hypoplasia: Findings from cardiac catheterization and the response to chronic therapy. Pediatr Crit Care Med. 2006 Nov; 7(6):589-94. PubMed
  • Jegatheesan P, Keller RL, Hawgood S. Early variable-flow nasal continuous positive airway pressure in infants < or =1000 grams at birth. J Perinatol. 2006 Mar; 26(3):189-96. PubMed
  • Jani J, Keller RL, Benachi A, Nicolaides KH, Favre R, Gratacos E, Laudy J, Eisenberg V, Eggink A, Vaast P, Deprest J, Antenatal-CDH-Registry Group. Prenatal prediction of survival in isolated left-sided diaphragmatic hernia. Ultrasound Obstet Gynecol. 2006 Jan; 27(1):18-22. PubMed
  • Grethel EJ, Cortes RA, Wagner AJ, Clifton MS, Lee H, Farmer DL, Harrison MR, Keller RL, Nobuhara KK. Prosthetic patches for congenital diaphragmatic hernia repair: Surgisis vs Gore-Tex. J Pediatr Surg. 2006 Jan; 41(1):29-33; discussion 29-33. PubMed
  • Keller RL, Tacy TA, Fields S, Ofenstein JP, Aranda JV, Clyman RI. Combined treatment with a nonselective nitric oxide synthase inhibitor (l-NMMA) and indomethacin increases ductus constriction in extremely premature newborns. Pediatr Res. 2005 Dec; 58(6):1216-21. PubMed
  • Slavotinek AM, Schauer G, Machin G, Dasouki M, Rueda-Pedraza ME, Chiricosta F, Keller R. Fryns syndrome: report of eight new cases. Genet Med. 2005 Jan; 7(1):74-6. PubMed
  • Cortes RA, Keller RL, Townsend T, Harrison MR, Farmer DL, Lee H, Piecuch RE, Leonard CH, Hetherton M, Bisgaard R, Nobuhara KK. Survival of severe congenital diaphragmatic hernia has morbid consequences. J Pediatr Surg. 2005 Jan; 40(1):36-45; discussion 45-6. PubMed
  • Keller RL, Hawgood S, Neuhaus JM, Farmer DL, Lee H, Albanese CT, Harrison MR, Kitterman JA. Infant pulmonary function in a randomized trial of fetal tracheal occlusion for severe congenital diaphragmatic hernia. Pediatr Res. 2004 Nov; 56(5):818-25. PubMed
  • Keller RL, Hamrick SE, Kitterman JA, Fineman JR, Hawgood S. Treatment of rebound and chronic pulmonary hypertension with oral sildenafil in an infant with congenital diaphragmatic hernia. Pediatr Crit Care Med. 2004 Mar; 5(2):184-7. PubMed
  • Harrison MR, Keller RL, Hawgood SB, Kitterman JA, Sandberg PL, Farmer DL, Lee H, Filly RA, Farrell JA, Albanese CT. A randomized trial of fetal endoscopic tracheal occlusion for severe fetal congenital diaphragmatic hernia. N Engl J Med. 2003 Nov 13; 349(20):1916-24. PubMed
  • Keller RL, Clyman RI. Persistent Doppler flow predicts lack of response to multiple courses of indomethacin in premature infants with recurrent patent ductus arteriosus. Pediatrics. 2003 Sep; 112(3 Pt 1):583-7. PubMed
  • Keller RL, Glidden DV, Paek BW, Goldstein RB, Feldstein VA, Callen PW, Filly RA, Albanese CT. The lung-to-head ratio and fetoscopic temporary tracheal occlusion: prediction of survival in severe left congenital diaphragmatic hernia. Ultrasound Obstet Gynecol. 2003 Mar; 21(3):244-9. PubMed
  • Keller RL, Aaroz PA, Hawgood S, Higgins CB. MR imaging of hepatic pulmonary fusion in neonates. AJR Am J Roentgenol. 2003 Feb; 180(2):438-40. PubMed
  • Zemp E, Elsasser S, Schindler C, Künzli N, Perruchoud AP, Domenighetti G, Medici T, Ackermann-Liebrich U, Leuenberger P, Monn C, Bolognini G, Bongard JP, Brändli O, Karrer W, Keller R, Schöni MH, Tschopp JM, Villiger B, Zellweger JP. Long-term ambient air pollution and respiratory symptoms in adults (SAPALDIA study). The SAPALDIA Team. Am J Respir Crit Care Med. 1999 Apr; 159(4 Pt 1):1257-66. PubMed
  • Flasko A, Patel H, Butchert A, Guthrie W, Fielding M, O'Shaughnessy T, Heppler L, Klein R, Garabadian C, Melkonian R, Durst FM, Barkett G, Spahl T, Biggs J, Morris L, Krajack R, Fronda M, Collins T, Garry J, Bixby G, Cusack B, Farrell J, Dean T, Miller D, Keller R. Managing TMD. J Am Dent Assoc. 1997 Feb; 128(2):146-7. PubMed
  • Keller R, Bassetti S, Keist R, Mülsch A, Klauser S. Induction of nitric oxide synthase is a necessary precondition for expression of tumor necrosis factor-independent tumoricidal activity by activated macrophages. Biochem Biophys Res Commun. 1992 May 15; 184(3):1364-71. PubMed
  • Hu DJ, Keller R, Fleming D. Communicating AIDS information to Hispanics: the importance of language and media preference. Am J Prev Med. 1989 Jul-Aug; 5(4):196-200. PubMed
  • Pfister M, Keller R. [Periodic nocturnal ventilation using an Emerson chest respirator as an alternative to permanent tracheostomy with positive pressure ventilation in patients with idiopathic scoliosis and severe global respiratory insufficiency]. Schweiz Med Wochenschr. 1988 Sep 24; 118(38):1371-4. PubMed
  • OH W, KELLER R, KLEIN RI, KUNSTADTER RH. ANTIBIOTICS IN INFANTS FOR PREMATURE RUPTURE OF MEMBRANES. STUDY OF PROPHYLACTIC USE IN PREMATURE INFANTS. Am J Dis Child. 1964 Aug; 108:149-53. PubMed
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